Type

Journal Article

Authors

Hugh Garavan
Marina Shpaner
John J Foxe
Robert Hester
A M Kelly

Subjects

Psychiatry

Topics
female image processing computer assisted brain evoked potentials male memory adult brain mapping humans cognition functional laterality physiology anatomy histology adolescent magnetic resonance imaging

Flexible cognitive control: effects of individual differences and brief practice on a complex cognitive task. (2005)

Abstract Brain activations underlying cognitive processes are subject to modulation as a result of increasing cognitive demands, individual differences, and practice. The present study investigated these modulatory effects in a cognitive control task which required inhibition of prepotent responses based on the contents of working memory (WM) and which enabled a novel dissociation of item-specific and task-skill effects resulting from brief practice. Distinct responses in areas underlying WM and inhibitory control in the absence of behavioral changes reflected different effects of item repetition and general task practice on tonic working memory and phasic inhibitory processes. Item repetition was associated with decreases in both unique and common areas subserving WM and inhibitory control. In contrast, general task practice was reflected in decreases in the level of tonic WM activity required to maintain a consistently high level of task performance but increased activity in a number of core inhibitory regions including dorsolateral and inferior PFC and inferior parietal cortex. Furthermore, both practice and individual differences in task performance were associated with the ability to modulate and maintain activity in frontostriatal areas mediating attentional control, suggesting that the areas that differ between individuals can be modulated by practice within an individual. These results raise the possibility that a fundamental human ability, reflexive cognitive control, is amenable to practice.
Collections Ireland -> Trinity College Dublin -> PubMed

Full list of authors on original publication

Hugh Garavan, Marina Shpaner, John J Foxe, Robert Hester, A M Kelly

Experts in our system

1
Hugh Garavan
Trinity College Dublin
Total Publications: 160
 
2
John J Foxe
Trinity College Dublin
Total Publications: 43
 
3
Robert Hester
Trinity College Dublin
Total Publications: 14
 
4
Aine Kelly
Trinity College Dublin
Total Publications: 6