Type

Journal Article

Authors

R Paul Ross
Paul D. Cotter
Colin Hill
Paula M. O'Connor
Harsh Mathur

Subjects

Medicine & Nursing

Topics
combinations clostridium difficile thuricin cd treatment vancomycin recurrence metronidazole clinical

Analysis of anti-Clostridium difficile activity of thuricin CD, vancomycin, metronidazole, ramoplanin, and actagardine, both singly and in paired combinations. (2013)

Abstract Due to the ongoing problem of recurrence of Clostridium difficile-associated diarrhea following antibiotic treatment, there is an urgent need for alternative treatment options. We assessed the MICs of five antimicrobials singly and in combinations against a range of C. difficile clinical isolates. Ramoplanin-actagardine combinations were particularly effective, with partial synergistic/additive effects observed against 61.5% of C. difficile strains tested.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

R Paul Ross, Paul D. Cotter, Colin Hill, Paula M. O'Connor, Harsh Mathur

Experts in our system

1
R Paul Ross
Teagasc
Total Publications: 441
 
2
Paul D. Cotter
Teagasc
Total Publications: 253
 
3
Colin Hill
University College Cork
Total Publications: 351
 
4
Paula M. O'Connor
Teagasc
Total Publications: 85
 
5
Harsh Mathur
University College Cork
Total Publications: 9