Type

Journal Article

Authors

Douwe van Sinderen
Mary O'Connell Motherway
Paul W O’ Toole
Sabrina Duranti
Ludovica F Buttó
Marco Ventura
Francesca Turroni

Subjects

Microbiology

Topics
this review probiotic bacteria lactobacillus human microbiota molecular gut microbiota health status bifidobacterium

Molecular dialogue between the human gut microbiota and the host: a Lactobacillus and Bifidobacterium perspective. (2012)

Abstract The human gut represents a highly complex ecosystem, which is densely colonized by a myriad of microorganisms that influence the physiology, immune function and health status of the host. Among the many members of the human gut microbiota, there are microorganisms that have co-evolved with their host and that are believed to exert health-promoting or probiotic effects. Probiotic bacteria isolated from the gut and other environments are commercially exploited, and although there is a growing list of health benefits provided by the consumption of such probiotics, their precise mechanisms of action have essentially remained elusive. Genomics approaches have provided exciting new opportunities for the identification of probiotic effector molecules that elicit specific responses to influence the physiology and immune function of their human host. In this review, we describe the current understanding of the intriguing relationships that exist between the human gut and key members of the gut microbiota such as bifidobacteria and lactobacilli, discussed here as prototypical groups of probiotic microorganisms.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Douwe van Sinderen, Mary O'Connell Motherway, Paul W O’ Toole, Sabrina Duranti, Ludovica F Buttó, Marco Ventura, Francesca Turroni

Experts in our system

1
Douwe van Sinderen
University College Cork
Total Publications: 61
 
2
Mary O'Connell Motherway
University College Cork
Total Publications: 18
 
3
Paul W O’ Toole
University College Cork
Total Publications: 92
 
4
Sabrina Duranti
University College Cork
 
5
Marco Ventura
University College Cork
Total Publications: 31
 
6
Francesca Turroni
University College Cork
Total Publications: 8