Type

Journal Article

Authors

Colin Hill
Paul Ross
Timothy G. Dinan
Fergus Shanahan

Subjects

Microbiology

Topics
molecular probiotics gut microbiota media bifidobacterium health disease lactobacillus

Probiotics in transition. (2012)

Abstract Despite the hyperbole often linked with a popular research field, the scientific rationale for probiotics is sound. The probiotic concept is not new but is undergoing transition as knowledge of the gut microbiota in health and disease becomes translated to the clinic. Operationally, a probiotic represents a mimic of and/or supplement to the normal gut microbiota. Much confusion has arisen among consumers because of media misportrayals of probiotics as all being the same. However, with clarification of the molecular basis of host-microbe interactions, the selection criteria for probiotics and the delineation of their distinct mechanisms of action are improving. Most probiotics are from the genus Lactobacillus or Bifidobacterium; this is likely to change and diversify. Similarly, the development of new therapeutic strategies, such as the development of phagebiotics, psychobiotics, and genetically modified pharmabiotics, is poised to become a therapeutic reality.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Colin Hill, Paul Ross, Timothy G. Dinan, Fergus Shanahan

Experts in our system

1
Colin Hill
University College Cork
Total Publications: 351
 
2
Paul Ross
University College Cork
Total Publications: 29
 
3
Fergus Shanahan
University College Cork
Total Publications: 237