Type

Journal Article

Authors

Paul W O’ Toole
R Paul Ross
Colin Hill
Fergus Shanahan
Anthony P Fitzgerald
Julian R Marchesi
Catherine Stanton
Lorraine Brennan
Martina Wallace
Douwe van Sinderen
and 16 others

Subjects

Medicine & Nursing

Topics
health health surveys cohort studies feces diet fruit statistics numerical data health status intestines hospitals community rehabilitation centers metagenome aging physiology aged 80 and over humans aged homes for the aged meat diet surveys vegetables questionnaires microbiology geriatric assessment

Gut microbiota composition correlates with diet and health in the elderly. (2012)

Abstract Alterations in intestinal microbiota composition are associated with several chronic conditions, including obesity and inflammatory diseases. The microbiota of older people displays greater inter-individual variation than that of younger adults. Here we show that the faecal microbiota composition from 178 elderly subjects formed groups, correlating with residence location in the community, day-hospital, rehabilitation or in long-term residential care. However, clustering of subjects by diet separated them by the same residence location and microbiota groupings. The separation of microbiota composition significantly correlated with measures of frailty, co-morbidity, nutritional status, markers of inflammation and with metabolites in faecal water. The individual microbiota of people in long-stay care was significantly less diverse than that of community dwellers. Loss of community-associated microbiota correlated with increased frailty. Collectively, the data support a relationship between diet, microbiota and health status, and indicate a role for diet-driven microbiota alterations in varying rates of health decline upon ageing.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Paul W O’ Toole, R Paul Ross, Colin Hill, Fergus Shanahan, Anthony P Fitzgerald, Julian R Marchesi, Catherine Stanton, Lorraine Brennan, Martina Wallace, Douwe van Sinderen and 16 others

Experts in our system

1
Paul W O’ Toole
University College Cork
Total Publications: 92
 
2
R Paul Ross
Teagasc
Total Publications: 441
 
3
Colin Hill
University College Cork
Total Publications: 351
 
4
Fergus Shanahan
University College Cork
Total Publications: 237
 
5
Anthony P Fitzgerald
University College Cork
Total Publications: 68
 
6
Julian R Marchesi
University College Cork
Total Publications: 40
 
7
Catherine Stanton
Teagasc
Total Publications: 261
 
8
Lorraine Brennan
University College Dublin
Total Publications: 143
 
9
Martina Wallace
University College Dublin
Total Publications: 4
 
10
Douwe van Sinderen
University College Cork