Type

Journal Article

Authors

Paul D. Cotter
Gerald F Fitzgerald
Colin Hill
R Paul Ross
Catherine Stanton
Sarah Norberg

Subjects

Microbiology

Topics
humans cronobacter cronobacter sakazakii isolation purification infant food food contamination infant formula infant microbiology food microbiology

Cronobacter spp. in powdered infant formula. (2012)

Abstract Cronobacter species are opportunistic pathogens, and a mortality rate of 40 to 80% is associated with infections. This pathogen can cause a range of serious diseases such as meningitis, septicemia, necrotizing enterocolitis, and brain abscesses and has been responsible for a variety of sequelae such as quadriplegia. Although Cronobacter can cause disease in both adults and infants, infant infections associated with powdered formula are the focus of this review. Since the first reported Cronobacter infection outbreak in 1958, powdered infant formula has been identified as a major source of these outbreaks, resulting in many recalls of powdered infant formula worldwide. This contamination has created an immense problem for the powdered infant formula industry. In this review, we discuss the taxonomy of Cronobacter species, the natural habitat of Cronobacter and its presence in foods, the physiology, pathogenicity, and virulence of Cronobacter species, and available detection methods. We also discuss reported cases of Cronobacter infection linked to powdered infant formula consumption and then focus specifically on the official World Health Organization guidelines for preparation of powdered infant formula.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Paul D. Cotter, Gerald F Fitzgerald, Colin Hill, R Paul Ross, Catherine Stanton, Sarah Norberg

Experts in our system

1
Paul D. Cotter
Teagasc
Total Publications: 253
 
2
Gerald F Fitzgerald
Teagasc
Total Publications: 207
 
3
Colin Hill
University College Cork
Total Publications: 351
 
4
R Paul Ross
Teagasc
Total Publications: 441
 
5
Catherine Stanton
Teagasc
Total Publications: 261