Type

Journal Article

Authors

Colin Hill
Ana Bernardo
Mercedes López
Winy Messens
Miguel Prieto
Maire Begley
Avelino Alvarez-Ordóñez

Subjects

Microbiology

Topics
acids stress physiological microbial viability gastrointestinal tract toxicity microbiology humans physiology drug effects salmonella bile acids and salts

Salmonella spp. survival strategies within the host gastrointestinal tract. (2011)

Abstract Human salmonellosis infections are usually acquired via the food chain as a result of the ability of Salmonella serovars to colonize and persist within the gastrointestinal tract of their hosts. In addition, after food ingestion and in order to cause foodborne disease in humans, Salmonella must be able to resist several deleterious stress conditions which are part of the host defence against infections. This review gives an overview of the main defensive mechanisms involved in the Salmonella response to the extreme acid conditions of the stomach, and the elevated concentrations of bile salts, osmolytes and commensal bacterial metabolites, and the low oxygen tension conditions of the mammalian and avian gastrointestinal tracts.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Colin Hill, Ana Bernardo, Mercedes López, Winy Messens, Miguel Prieto, Maire Begley, Avelino Alvarez-Ordóñez

Experts in our system

1
Colin Hill
University College Cork
Total Publications: 351
 
2
Maire Begley
University College Cork
Total Publications: 27
 
3
Avelino Alvarez-Ordóñez
University College Cork
Total Publications: 6