Type

Journal Article

Authors

R Paul Ross
Paul D. Cotter
Colin Hill
Srinivas Suda

Subjects

Microbiology

Topics
drug effects molecular structure bacteria pharmacology molecular sequence data amino acid sequence structure activity relationship bacteriocins anti bacterial agents chemistry

Investigating the importance of charged residues in lantibiotics. (2010)

Abstract Lantibiotics are antimicrobial peptides which can have a broad spectrum activity against many Gram positive pathogens. Many of these peptides contain charged amino acids which may be of critical importance with respect to antimicrobial activity. We have recently carried out an in-depth bioengineering based investigation of the importance of charged residues in a representative two peptide lantibiotic, lacticin 3147, and here we discuss the significance of these findings in the context of other lantibiotics and cationic antimicrobial peptides.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

R Paul Ross, Paul D. Cotter, Colin Hill, Srinivas Suda

Experts in our system

1
R Paul Ross
Teagasc
Total Publications: 441
 
2
Paul D. Cotter
Teagasc
Total Publications: 253
 
3
Colin Hill
University College Cork
Total Publications: 351