Journal Article


Alan Dw Dobson
Julian R Marchesi
Jonathan Kennedy



novel the genes metagenomics culture enzymes approaches microbial communities marine environments

Marine metagenomics: strategies for the discovery of novel enzymes with biotechnological applications from marine environments. (2008)

Abstract Metagenomic based strategies have previously been successfully employed as powerful tools to isolate and identify enzymes with novel biocatalytic activities from the unculturable component of microbial communities from various terrestrial environmental niches. Both sequence based and function based screening approaches have been employed to identify genes encoding novel biocatalytic activities and metabolic pathways from metagenomic libraries. While much of the focus to date has centred on terrestrial based microbial ecosystems, it is clear that the marine environment has enormous microbial biodiversity that remains largely unstudied. Marine microbes are both extremely abundant and diverse; the environments they occupy likewise consist of very diverse niches. As culture-dependent methods have thus far resulted in the isolation of only a tiny percentage of the marine microbiota the application of metagenomic strategies holds great potential to study and exploit the enormous microbial biodiversity which is present within these marine environments.
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Full list of authors on original publication

Alan Dw Dobson, Julian R Marchesi, Jonathan Kennedy

Experts in our system

Alan D W Dobson
University College Cork
Total Publications: 116
Julian R Marchesi
University College Cork
Total Publications: 45
Jonathan Kennedy
University College Cork
Total Publications: 33