Journal Article


Colin Hill
Roy D. Sleator



therapeutic use genetic engineering bacterial physiological phenomena drug delivery systems probiotics humans bacteria drug stability pathogenicity genetics animals cells cultured administration dosage drug storage biotechnology

Engineered pharmabiotics with improved therapeutic potential. (2008)

Abstract Although described for over a century, scientists and clinicians alike are only now beginning to realize the significant medical applications of probiotic cultures. Given the increasing commercial and clinical relevance of probiotics, improving their stress tolerance profile and ability to overcome the physiochemical defences of the host is an important biological goal. Patho-biotechnology describes the application of pathogen derived (ex vivo and in vivo) stress survival strategies for the design of more technologically robust and effective probiotic cultures with improved biotechnological and clinical applications as well as the development of novel vaccine and drug delivery platforms.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Colin Hill, Roy D. Sleator

Experts in our system

Colin Hill
University College Cork
Total Publications: 351
Roy D. Sleator
University College Cork
Total Publications: 44