Type

Journal Article

Authors

Douwe van Sinderen
Gerald F Fitzgerald
Sylvain Moineau
Carlos Canchaya
Marco Ventura
Stephen Mc Grath
Hélène Deveau
Jennifer Mahony

Subjects

Microbiology

Topics
bacteriophages viral plaque assay lactococcus lactis siphoviridae virology replication origin molecular sequence data genetic variation physiology europe sequence analysis dna bacterial proteins genome viral genetics base sequence

Sequence and comparative genomic analysis of lactococcal bacteriophages jj50, 712 and P008: evolutionary insights into the 936 phage species. (2006)

Abstract The complete genome sequences of three lactococcal 936-type bacteriophages, 712, jj50 and P008, were determined. Comparative genomic analysis of these phages with the previously sequenced 936-type phages, sk1 and bIL170, reveals a strict conservation of the overall genetic organization of this geographically diverse phage group. Genetic divergence was mainly observed in the early expressed region of the phage genomes, where a number of deletions, exchanges and insertions appear to have occurred. These genetic differences may be responsible for the observed differential sensitivity to the lactococcal DNA injection blocking protein, Sie(2009), and the abortive infection system, AbiA.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Douwe van Sinderen, Gerald F Fitzgerald, Sylvain Moineau, Carlos Canchaya, Marco Ventura, Stephen Mc Grath, Hélène Deveau, Jennifer Mahony

Experts in our system

1
Douwe van Sinderen
University College Cork
Total Publications: 61
 
2
Gerald F Fitzgerald
Teagasc
Total Publications: 208
 
3
Marco Ventura
University College Cork
Total Publications: 31
 
4
Jennifer Mahony
University College Cork
Total Publications: 71