Type

Journal Article

Authors

Colin Hill
Cormac G M Gahan
Maire Begley

Subjects

Microbiology

Topics
growth development animals drug effects genetics bacterial infections bile acids and salts gastrointestinal tract microbiology humans bacteria pharmacology pathogenicity

The interaction between bacteria and bile. (2004)

Abstract Commensal and pathogenic microorganisms must resist the deleterious actions of bile in order to survive in the human gastrointestinal tract. Herein we review the current knowledge on the mechanisms by which Gram-positive and Gram-negative bacteria contend with bile stress. We describe the antimicrobial actions of bile, assess the variations in bile tolerance between bacterial genera and examine the interplay between bile stress and other stresses. The molecular mechanisms underlying bile tolerance are investigated and the relationship between bile and virulence is examined. Finally, the potential benefits of bile research are briefly discussed.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Colin Hill, Cormac G M Gahan, Maire Begley

Experts in our system

1
Colin Hill
University College Cork
Total Publications: 351
 
2
Cormac G M Gahan
University College Cork
Total Publications: 109
 
3
Maire Begley
University College Cork
Total Publications: 27