Journal Article


Colin Hill
Paul D. Cotter



bacillus cereus metabolism listeria monocytogenes mycobacterium clostridium perfringens rhodococcus equi growth development proton pumps hydrogen ion concentration lactobacillus physiology gram positive bacteria staphylococcus aureus food microbiology

Surviving the acid test: responses of gram-positive bacteria to low pH. (2003)

Abstract Gram-positive bacteria possess a myriad of acid resistance systems that can help them to overcome the challenge posed by different acidic environments. In this review the most common mechanisms are described: i.e., the use of proton pumps, the protection or repair of macromolecules, cell membrane changes, production of alkali, induction of pathways by transcriptional regulators, alteration of metabolism, and the role of cell density and cell signaling. We also discuss the responses of Listeria monocytogenes, Rhodococcus, Mycobacterium, Clostridium perfringens, Staphylococcus aureus, Bacillus cereus, oral streptococci, and lactic acid bacteria to acidic environments and outline ways in which this knowledge has been or may be used to either aid or prevent bacterial survival in low-pH environments.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Colin Hill, Paul D. Cotter

Experts in our system

Colin Hill
University College Cork
Total Publications: 351
Paul D. Cotter
Total Publications: 253