Journal Article


C Hill
C G Gahan
N Emerson
P D Cotter



protein kinases colony count microbial listeriosis gene deletion bacterial proteins microbiology genetics genes bacterial animals molecular sequence data pathogenicity signal transduction listeria monocytogenes mice inbred balb c virulence growth development mice protein histidine kinase heat shock response

Identification and disruption of lisRK, a genetic locus encoding a two-component signal transduction system involved in stress tolerance and virulence in Listeria monocytogenes. (1999)

Abstract lisRK encodes a two-component regulatory system in the food pathogen Listeria monocytogenes LO28. Following identification of the operon in an acid-tolerant Tn917 mutant, a deletion in the histidine kinase component was shown to result in a growth phase variation in acid tolerance, an ability to grow in high ethanol concentrations, and a significant reduction in virulence.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

C Hill, C G Gahan, N Emerson, P D Cotter

Experts in our system

Colin Hill
University College Cork
Total Publications: 351
Cormac G M Gahan
University College Cork
Total Publications: 109
Paul D. Cotter
Total Publications: 253