Type

Journal Article

Authors

David Soto
Kleio Vidaki
Ciara M. Greene

Subjects

Psychiatry

Topics
substrates processing recognition prefrontal cortex functional connectivity memory hippocampus network

Fractionating the neural substrates of incidental recognition memory. (2014)

Abstract Familiar stimuli are typically accompanied by decreases in neural response relative to the presentation of novel items, but these studies often include explicit instructions to discriminate old and new items; this creates difficulties in partialling out the contribution of top-down intentional orientation to the items based on recognition goals. Here, we used an incidental recognition functional MRI paradigm to compare response to repetition of novel and familiar stimuli in the absence of any ongoing memory task demand. The inferior frontal gyrus and hippocampus both displayed enhanced response to novelty and suppressed response to familiar stimuli, notably, under conditions which did not encourage intentional orientation to recognize novel or old items. Functional connectivity analyses additionally suggested that familiarity processing is associated with a network incorporating the hippocampus and prefrontal cortex. We conclude that recognition memory substrates can be fractionated even in the absence of memory goals.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

David Soto, Kleio Vidaki, Ciara M. Greene

Experts in our system

1
Ciara M. Greene
University College Cork
Total Publications: 24