Type

Journal Article

Authors

Lorraine Brennan
Eileen R Gibney
Michael J Gibney
Albert Flynn
Janette Walton
Breige McNulty
Anne P Nugent
Marianne C Walsh
Clare B O'Donovan

Subjects

Agriculture & Food Science

Topics
national nutrition survey delivery cluster analysis blood pressure k means clustering nutrition cholesterol hdl decision tree

Use of metabotyping for the delivery of personalised nutrition. (2014)

Abstract Personalised nutrition can be defined as dietary advice that is tailored to an individual. In recent years, the concept of targeted nutrition has evolved, which involves delivering specific dietary advice to a group of phenotypically similar individuals or metabotypes. This study examined whether cluster analysis could be used to define metabotypes and developed a strategy for the delivery of targeted dietary advice. K-means clustering was employed to identify clusters based on four markers of metabolic health (triacylglycerols, total cholesterol, direct HDL cholesterol and glucose) (n = 896) using data from the National Adult Nutrition Survey. A decision tree approach was developed for the delivery of targeted dietary advice per cluster based on biochemical characteristics, anthropometry and blood pressure. The appropriateness of the advice was tested by comparison with individualised dietary advice manually compiled (n = 99). A mean match of 89.1% between the methods was demonstrated with a 100% match for two-thirds of participants. Good agreement was found between the individualised and targeted methods demonstrating the ability of this framework to deliver targeted dietary advice. This approach has the potential to be a fast and novel method for the delivery of targeted nutrition in clinical settings.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

Lorraine Brennan, Eileen R Gibney, Michael J Gibney, Albert Flynn, Janette Walton, Breige McNulty, Anne P Nugent, Marianne C Walsh, Clare B O'Donovan

Experts in our system

1
Lorraine Brennan
University College Dublin
Total Publications: 166
 
2
Eileen R Gibney
University College Dublin
Total Publications: 98
 
3
Michael J Gibney
University College Dublin
Total Publications: 102
 
4
Albert Flynn
University College Cork
Total Publications: 83
 
5
Janette Walton
University College Cork
Total Publications: 79
 
6
Breige A McNulty
University College Cork
 
7
Anne P Nugent
University College Cork
 
8
Marianne C Walsh
University College Dublin
Total Publications: 51
 
9
Clare B O'Donovan
University College Dublin
Total Publications: 30