Type

Journal Article

Authors

Shawn Marshall
Michael D Cusimano
Susan Brien
Michael D. Gilchrist
T Blaine Hoshizaki
Janie Cournoyer
David Koncan
Marshall Kendall
Andrew Post

Subjects

Engineering

Topics
north america brain tissue grey matter white matter brain injuries finite element methods finite element modelling injury reconstruction

Characterization of persistent concussive syndrome using injury reconstruction and finite element modelling. (2014)

Abstract Concussions occur 1.7 million times a year in North America, and account for approximately 75% of all traumatic brain injuries (TBI). Concussions usually cause transient symptoms but 10 to 20% of patients can have symptoms that persist longer than a month. The purpose of this research was to use reconstructions and finite element modeling to determine the brain tissue stresses and strains that occur in impacts that led to persistent post concussive symptoms (PCS) in hospitalized patients. A total of 21 PCS patients had their head impacts reconstructed using computational, physical and finite element methods. The dependent variables measured were maximum principal strain, von Mises stress (VMS), strain rate, and product of strain and strain rate. For maximum principal strain alone there were large regions of brain tissue incurring 30 to 40% strain. This large field of strain was also evident when using strain rate, product of strain and strain rate. In addition, VMS also showed large magnitudes of stress throughout the cerebrum tissues. The distribution of strains throughout the brain tissues indicated peak responses were always present in the grey matter (0.481), with the white matter showing significantly lower strains (0.380) (p<0.05). The impact conditions of the PCS cases were severe in nature, with impacts against non-compliant surfaces (concrete, steel, ice) resulting in higher brain deformation. PCS biomechanical parameters were shown to fit between those that have been shown to cause transient post concussive symptoms and those that lead to actual pathologic damage like contusion, however, values of all metrics were characterized by large variance and high average responses. This data supports the theory that there exists a progressive continuum of impacts that lead to a progressive continuum of related severity of injury from transient symptoms to pathological damage.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

Shawn Marshall, Michael D Cusimano, Susan Brien, Michael D. Gilchrist, T Blaine Hoshizaki, Janie Cournoyer, David Koncan, Marshall Kendall, Andrew Post

Experts in our system

1
Shawn Marshall
University College Dublin
Total Publications: 5
 
2
Michael D Cusimano
University College Dublin
Total Publications: 6
 
3
Susan Brien
University College Dublin
Total Publications: 5
 
4
M. D. Gilchrist
University College Dublin
Total Publications: 172
 
5
Thomas Blaine Hoshizaki
University College Dublin
Total Publications: 31
 
6
David Koncan
University College Dublin
Total Publications: 3
 
7
Marshall Kendall
University College Dublin
Total Publications: 3
 
8
Andrew Post
University College Dublin
Total Publications: 29