Type

Journal Article

Authors

Fionnuala M McAuliffe
Jean M Donnelly
Eileen R Gibney
Ciara A McGowan
Mary K Horan

Subjects

Medicine & Nursing

Topics
pregnancy female prevention control glycemic index dietary carbohydrates metabolism fatty acids unsaturated fatty acids monounsaturated body weight maternal nutritional physiological phenomena dietary fats dietary proteins questionnaires weight gain food habits diet adiposity glucose tolerance test administration dosage body mass index fatty acids linear models blood glucose postprandial period infant life style adult body height humans fetal macrosomia energy intake diet records

Maternal low glycaemic index diet, fat intake and postprandial glucose influences neonatal adiposity--secondary analysis from the ROLO study. (2014)

Abstract The in utero environment is known to affect fetal development however many of the mechanisms by which this occurs remain unknown. The aim of this study was to examine the association between maternal dietary macronutrient intake and lifestyle throughout pregnancy and neonatal weight and adiposity. This was an analysis of 542 mother and infant pairs from the ROLO study (Randomised cOntrol trial of LOw glycaemic index diet versus no dietary intervention to prevent recurrence of fetal macrosomia). Food diaries as well as food frequency and lifestyle and physical activity questionnaires were completed during pregnancy. Maternal anthropometry was measured throughout pregnancy and neonatal anthropometry was measured at birth. Multiple linear regression analysis revealed the main maternal factor associated with increased birth weight was greater gestational weight gain R2adj 23.3% (F = 11.547, p < 0.001). The main maternal factor associated with increased birth length was non-smoking status R2adj 27.8% (F = 6.193, p < 0.001). Neonatal central adiposity (determined using waist:length ratio) was negatively associated with maternal age, and positively associated with the following parameters: smoking status, maternal pre-pregnancy arm circumference, percentage energy from saturated fat in late pregnancy, postprandial glucose at 28 weeks gestation and membership of the control group with a positive trend towards association with trimester 2 glycaemic load R2adj 38.1% (F = 8.000, p < 0.001). Several maternal diet and lifestyle factors were associated with neonatal anthropometry . Low glycaemic index dietary intervention in pregnancy was found to have a beneficial effect on neonatal central adiposity. Additionally, central adiposity was positively associated with maternal dietary fat intake and postprandial glucose highlighting the important role of healthy diet in pregnancy in promoting normal neonatal adiposity. Current Controlled Trials ISRCTN54392969.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

Fionnuala M McAuliffe, Jean M Donnelly, Eileen R Gibney, Ciara A McGowan, Mary K Horan

Experts in our system

1
Fionnuala M McAuliffe
University College Dublin
Total Publications: 176
 
2
Jean M Donnelly
University College Dublin
 
3
Eileen R Gibney
University College Dublin
Total Publications: 98
 
4
Ciara A McGowan
University College Dublin
 
5
Mary K Horan
University College Dublin
Total Publications: 11