Type

Journal Article

Authors

P A J Brama
S Ennis
D. E. MacHugh
P R van Weeren
J H Knaap
J A M van Arendonk
B J Ducro
E M van Grevenhof
J Conroy
P Govindarajan
and 3 others

Subjects

Veterinary

Topics
chromosome 10 genome wide association study genome association study susceptibility chromosomes horses loci

Genome-wide association study of osteochondrosis in the tarsocrural joint of Dutch Warmblood horses identifies susceptibility loci on chromosomes 3 and 10. (2012)

Abstract Equine osteochondrosis is a developmental joint disease that is a significant source of morbidity affecting multiple breeds of horse. The genetic variants underlying osteochondrosis susceptibility have not been established. Here, we describe the results of a genome-wide association study of osteochondrosis using 90 cases and 111 controls from a population of Dutch Warmblood horses. We report putative associations between osteochondrosis and loci on chromosome 3 (BIEC2-808543; P = 5.03 × 10(-7) ) and chromosome 10 (BIEC2-121323; P = 2.62 × 10(-7) ).
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

P A J Brama, S Ennis, D. E. MacHugh, P R van Weeren, J H Knaap, J A M van Arendonk, B J Ducro, E M van Grevenhof, J Conroy, P Govindarajan and 3 others

Experts in our system

1
P A J Brama
University College Dublin
Total Publications: 20
 
2
Sean Ennis
University College Dublin
Total Publications: 52
 
3
David E. MacHugh
University College Dublin
Total Publications: 80
 
4
P R van Weeren
University College Dublin
Total Publications: 6
 
5
Judith Conroy
University College Dublin
Total Publications: 24