Type

Journal Article

Authors

Lorraine Brennan
Anne P Nugent
Michael J Gibney
William D Fraser
John Collier
Aifric O'Sullivan
Louise O'Mahony
Magdalena Stepien

Subjects

Physiotherapy & Sport

Topics
metabolic syndrome food consumption adults mushrooms plasminogen activator inhibitor 1 vitamin d supplementation vitamin d deficiency

Effect of supplementation with vitamin D2-enhanced mushrooms on vitamin D status in healthy adults. (2012)

Abstract Vitamin D deficiency is emerging worldwide and many studies now suggest its role in the development of several chronic diseases. Due to the low level of vitamin D naturally occurring in food there is a need for supplementation and use of vitamin D-enhanced products. The aim of the present study was to determine if daily consumption of vitamin D2-enhanced mushrooms increased vitamin D status in free-living healthy adults or affected markers of the metabolic syndrome. A total of ninety volunteers (aged 40-65 years) were randomly assigned to one of two 4-week studies: mushroom study (15 µg vitamin D2 or placebo mushroom powder) and capsule study (15 µg vitamin D3 or placebo capsules). Consumption of vitamin D2-enhanced mushrooms increased serum 25-hydroxyvitamin D2 (25(OH)D2) by 128 % from baseline (3·9 (sd 1·9) nmol/l; P < 0·05). Serum 25(OH)D3 increased significantly in the vitamin D3 capsule group (a 55 % increase from a baseline of 44.0 (sd 17·1) nmol/l; P < 0·05). Vitamin D status (25(OH)D) was affected only in the vitamin D3 group. Plasminogen activator inhibitor-1 was lowered by vitamin D2 intake. Vitamin D2 from enhanced mushrooms was bioavailable and increased serum 25(OH)D2 concentration with no significant effect on 25(OH)D3 or total 25(OH)D.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

Lorraine Brennan, Anne P Nugent, Michael J Gibney, William D Fraser, John Collier, Aifric O'Sullivan, Louise O'Mahony, Magdalena Stepien

Experts in our system

1
Lorraine Brennan
University College Dublin
Total Publications: 166
 
2
Anne P Nugent
University College Cork
 
3
Michael J Gibney
University College Dublin
Total Publications: 102
 
4
Aifric O'Sullivan
University College Dublin
Total Publications: 11