Type

Journal Article

Authors

Mélanie Ottenio
Michael D. Gilchrist
Michel Destrade
Karine Bruyère
Aisling Ní Annaidh

Subjects

Microbiology

Topics
collagen aged 80 and over regression analysis anisotropy mechanical processes skin male biomechanics metabolism dermis humans cytology female

Characterization of the anisotropic mechanical properties of excised human skin. (2011)

Abstract The mechanical properties of skin are important for a number of applications including surgery, dermatology, impact biomechanics and forensic science. In this study, we have investigated the influence of location and orientation on the deformation characteristics of 56 samples of excised human skin. Uniaxial tensile tests were carried out at a strain rate of 0.012 s(-1) on skin from the back. Digital Image Correlation was used for 2D strain measurement and a histological examination of the dermis was also performed. The mean ultimate tensile strength (UTS) was 21.6±8.4 MPa, the mean failure strain 54%±17%, the mean initial slope 1.18±0.88 MPa, the mean elastic modulus 83.3±34.9 MPa and the mean strain energy was 3.6±1.6 MJ/m(3). A multivariate analysis of variance has shown that these mechanical properties of skin are dependent upon the orientation of the Langer lines (P<0.0001-P=0.046). The location of specimens on the back was also found to have a significant effect on the UTS (P=0.0002), the elastic modulus (P=0.001) and the strain energy (P=0.0052). The histological investigation concluded that there is a definite correlation between the orientation of the Langer lines and the preferred orientation of collagen fibres in the dermis (P<0.001). The data obtained in this study will provide essential information for those wishing to model the skin using a structural constitutive model.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

Mélanie Ottenio, Michael D. Gilchrist, Michel Destrade, Karine Bruyère, Aisling Ní Annaidh

Experts in our system

1
M. D. Gilchrist
University College Dublin
Total Publications: 172
 
2
Michel Destrade
National University of Ireland Galway
Total Publications: 106
 
3
Aisling Ní Annaidh
University College Dublin
Total Publications: 17