Type

Journal Article

Authors

L A L Corner
D O'Meara
E. Costello
E Gormley
D Murphy

Subjects

Microbiology

Topics
female mycobacterium bovis diagnosis microbiology animals veterinary bacteriological techniques male epidemiology age factors lung ireland tuberculosis mustelidae prevalence

The prevalence and distribution of Mycobacterium bovis infection in European badgers (Meles meles) as determined by enhanced post mortem examination and bacteriological culture. (2009)

Abstract The accurate diagnosis of Mycobacterium bovis infection in badgers is key to understanding the epidemiology of tuberculosis in this species and has significant implications for devising strategies to limit spread of the disease. In this study, badgers (n=215) in the Republic of Ireland were examined at post mortem and tissues were collected from a range of anatomical locations and pooled into groups for bacterial culture of M. bovis. By assessing confirmed gross visible lesions (VL) alone, infection was detected in 12.1% of badgers. However, by including the results of all culture positive pooled samples, the overall infection prevalence increased significantly to 36.3%. Two-thirds (66.7%) of infected animals had no visible lesions (NVL). While the thoracic cavity (lungs and pulmonary lymph nodes) was found to be the most common site of infection, in a proportion of animals infection was absent from the lungs and draining lymph nodes and was confined to the lymph nodes of the carcase or the head. This may indicate an early extrapulmonary dissemination of infection or alternatively, in the case of the head lymph nodes, a secondary pathogenic pathway involving the lymphoid tissues of the upper respiratory tract (URT).
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

L A L Corner, D O'Meara, E. Costello, E Gormley, D Murphy

Experts in our system

1
L A L Corner
University College Dublin
Total Publications: 34
 
2
Eamon Costello
Dublin City University
Total Publications: 94
 
3
E Gormley
University College Dublin
Total Publications: 68
 
4
Denise Murphy
University College Dublin
Total Publications: 13