Type

Journal Article

Authors

A.C.O. Evans
D Corcoran
T Fair
P. Lonergan

Subjects

Biochemistry

Topics
embryology animals pregnancy female embryo transfer cattle genetics embryo culture techniques male gene expression regulation developmental veterinary embryonic development culture media fertilization in vitro physiology

Effect of culture environment on gene expression and developmental characteristics in IVF-derived embryos. (2005)

Abstract It is generally accepted that mammalian preimplantation embryos are sensitive to their environment and that conditions of culture can affect future growth and developmental potential both pre- and postnatally. Evidence suggests that while culture conditions during bovine in vitro embryo production can impact somewhat on the developmental potential of the early embryo, the intrinsic quality of the oocyte is the key factor determining the proportion of oocytes developing to the blastocyst stage. In addition, evidence suggests that the period of post fertilization embryo culture is the most critical period affecting blastocyst quality assessed in terms of cryotolerance, gene expression pattern and ability to establish a pregnancy. This paper reviews the current literature, with emphasis on the bovine model, demonstrating evidence for an effect of post fertilization culture environment on embryo gene expression and quality.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

A.C.O. Evans, D Corcoran, T Fair, P. Lonergan

Experts in our system

1
A.C.O. Evans
University College Dublin
Total Publications: 92
 
2
T Fair
University College Dublin
Total Publications: 66
 
3
P. Lonergan
University College Dublin
Total Publications: 190