Type

Journal Article

Authors

P Raleigh
D Toolan
M McElroy
F Ehrensperger
M Vandevelde
R Fatzer
G Mulcahy
C T Mooney
J J Callanan

Subjects

Veterinary

Topics
brain male animals female veterinary organ specificity palatine tonsil pathology dog diseases spinal cord meningoencephalitis dogs

A novel nonsuppurative meningoencephalitis in young greyhounds in Ireland. (2002)

Abstract Fourteen 4- to 18-month-old vaccinated Greyhounds (10 males, 4 females) from three kennels in southern Ireland presented over a 2-year period with acute or insidious onset neurological signs. Head tilting, ataxia, recumbency, circling, and blindness were commonly observed, and animals were dull, dehydrated, and had lost weight. Hematologic and biochemical parameters reflected dehydration but were otherwise unremarkable. Microscopic examination revealed severe diffuse and focal gliosis and gemistocytosis accompanied by mononuclear cell perivascular cuffing in caudate nucleus and cortical gray matter of the cerebrum and in the periventricular gray matter of the anterior brainstem. Milder lesions were noted in the caudal brainstem, cranial spinal cord, and in the molecular layer of the cerebellum. This was accompanied by a lymphocyte and plasma cell infiltration of the cerebral and cerebellar meninges. Demyelination, neuropil necrosis, neuronophagia, and vasculitis were not observed. No inclusion bodies, fungi, or protozoal cysts were seen. Additional serologic and molecular pathology tests also failed to determine a cause, suggesting that these cases may represent a previously undiagnosed condition in the dog.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

P Raleigh, D Toolan, M McElroy, F Ehrensperger, M Vandevelde, R Fatzer, G Mulcahy, C T Mooney, J J Callanan

Experts in our system

1
Máire C McElroy
Teagasc
Total Publications: 28
 
2
G Mulcahy
University College Dublin
Total Publications: 91
 
3
Catherine Mooney
University College Dublin
Total Publications: 63
 
4
John J Callanan
University College Dublin
Total Publications: 60