Type

Journal Article

Authors

Michael Gill
Gary (James) Donohoe
Derek Williams Morris
Barry Green
Aiden Peter Corvin
Stephen Meredith
Ian Robertson
Sarah Clarke
Richard Reilly
Hugh Patrick Garavan

Subjects

Psychiatry

Topics
choice behavior patients male inhibition psychology perceptual disorders physiology middle aged space perception saccades schizophrenia neuropsychological tests etiology complications inhibitory control statistics numerical data specific verbal behavior attention humans adult memory short term female response inhibition spatial working memory psychology multiple regression analysis

Do antisaccade deficits in schizophrenia provide evidence of a specific inhibitory function? (2006)

Abstract Background: Despite its inhibitory control requirements, antisaccade deficits have been consistently associated with working memory impairments in schizophrenia. We investigated whether variance in antisaccade per formance could be better accounted for in terms of a specific inhibitory function. Method: We assessed 48 clinically stable out-patients with schizophrenia on an antisaccade task, as well as on measures of spatial and verbal working memory, sustained selective attention, and a simple motoric go 0 no-go measure of response inhibition. Results: In a stepwise multiple regression analysis, go 0 no-go task per formance accounted for a considerably greater percentage of variance in antisaccade per formance (25.3%) than either working memory (8.4%) or sustained selective attention task (9.1%). Discussion: We conclude that antisaccade deficits in schizophrenia appear to be better understood in terms of a specific deficit of inhibitory control than in terms of more general difficulties with context maintenance or goal neglect.
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Full list of authors on original publication

Michael Gill, Gary (James) Donohoe, Derek Williams Morris, Barry Green, Aiden Peter Corvin, Stephen Meredith, Ian Robertson, Sarah Clarke, Richard Reilly, Hugh Patrick Garavan

Experts in our system

1
Michael Gill
Trinity College Dublin
Total Publications: 260
 
2
Gary Donohoe
Trinity College Dublin
Total Publications: 130
 
3
Derek Morris
Trinity College Dublin
Total Publications: 150
 
4
Aiden Corvin
Trinity College Dublin
Total Publications: 190
 
5
Ian H Robertson
Trinity College Dublin
Total Publications: 142
 
6
Richard Reilly
Trinity College Dublin
Total Publications: 183
 
7
Hugh Garavan
Trinity College Dublin
Total Publications: 160