Type

Journal Article

Authors

Hugh Patrick Garavan

Subjects

Psychology

Topics
age patterns response inhibition older adults young adults inhibitory control psychology mri

Comparability of functional MRI response in young and old during inhibition (2004)

Abstract AB When using fMRI to study age-related cognitive changes, it is important to establish the integrity of the hemodynamic response because, potentially, it can be affected by age and disease. However, there have been few attempts to document such integrity and no attempts using higher cognitive rather than perceptual or motor tasks. We used fMRI with 28 healthy young and older adults on an inhibitory control task. Although older and young adults differed in task performance and activation patterns, they had comparable hemodynamic responses. We conclude that activation during cognitive inhibition, which was predominantly increased in elders, was not due to vascular confounds or specific changes in hemodynamic coupling.
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Full list of authors on original publication

Hugh Patrick Garavan

Experts in our system

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Hugh Garavan
Trinity College Dublin
Total Publications: 160