Type

Journal Article

Authors

Marco Ventura
Douwe van Sinderen
Abelardo Margolles
Nicola Segata
Diego Mora
Rita Hickey
Doyle V Ward
Jonathan Lane
Borja Sanchez
Stefania Arioli
and 10 others

Subjects

Agriculture & Food Science

Topics
gut microbiota bifidobacteria adult human carbohydrate gut social behavior resource sharing microbial consortium

Bifidobacteria exhibit social behavior through carbohydrate resource sharing in the gut. (2015)

Abstract Bifidobacteria are common and frequently dominant members of the gut microbiota of many animals, including mammals and insects. Carbohydrates are considered key carbon sources for the gut microbiota, imposing strong selective pressure on the complex microbial consortium of the gut. Despite its importance, the genetic traits that facilitate carbohydrate utilization by gut microbiota members are still poorly characterized. Here, genome analyses of 47 representative Bifidobacterium (sub)species revealed the genes predicted to be required for the degradation and internalization of a wide range of carbohydrates, outnumbering those found in many other gut microbiota members. The glycan-degrading abilities of bifidobacteria are believed to reflect available carbon sources in the mammalian gut. Furthermore, transcriptome profiling of bifidobacterial genomes supported the involvement of various chromosomal loci in glycan metabolism. The widespread occurrence of bifidobacterial saccharolytic features is in line with metagenomic and metatranscriptomic datasets obtained from human adult/infant faecal samples, thereby supporting the notion that bifidobacteria expand the human glycobiome. This study also underscores the hypothesis of saccharidic resource sharing among bifidobacteria through species-specific metabolic specialization and cross feeding, thereby forging trophic relationships between members of the gut microbiota.
Collections Ireland -> Teagasc -> PubMed

Full list of authors on original publication

Marco Ventura, Douwe van Sinderen, Abelardo Margolles, Nicola Segata, Diego Mora, Rita Hickey, Doyle V Ward, Jonathan Lane, Borja Sanchez, Stefania Arioli and 10 others

Experts in our system

1
Marco Ventura
University College Cork
Total Publications: 31
 
2
Douwe van Sinderen
University College Cork
 
3
Abelardo Margolles
University College Cork
 
4
Rita M. Hickey
Teagasc
Total Publications: 24
 
5
Borja Sanchez
Teagasc