Type

Other / n/a

Authors

Eduardo Ruiz-Hernández
Garry P Duffy
Wim E Hennink
Gert Storm
Fergal O'Brien
Kathleen E O'Donnell
Burcin Ozbakir
Conn L Hastings
Adolfo López-Noriega

Subjects

Biochemistry

Topics
hydrogel chitosan doxorubicin cell line cell survival glycerophosphates cell line tumor anatomy liposomes humans tumor

Hyperthermia-induced drug delivery from thermosensitive liposomes encapsulated in an injectable hydrogel for local chemotherapy. (2014)

Abstract A novel drug delivery system, enabling an in situ, thermally triggered drug release is described, consisting of an injectable thermoresponsive chitosan hydrogel containing doxorubicin-loaded thermosensitive liposomes. The design, fabrication, characterization, and an assessment of in vitro bioactivity of this formulation is detailed. Combining on-demand drug delivery with in situ gelation results in a promising candidate for local chemotherapy.
Collections Ireland -> Royal College of Surgeons in Ireland -> Anatomy Articles
Ireland -> Royal College of Surgeons in Ireland -> Department of Anatomy

Full list of authors on original publication

Eduardo Ruiz-Hernández, Garry P Duffy, Wim E Hennink, Gert Storm, Fergal O'Brien, Kathleen E O'Donnell, Burcin Ozbakir, Conn L Hastings, Adolfo López-Noriega

Experts in our system

1
Eduardo Ruiz-Hernández
Royal College of Surgeons in Ireland
Total Publications: 8
 
2
Garry P Duffy
Royal College of Surgeons in Ireland
Total Publications: 54
 
3
Wim E Hennink
Royal College of Surgeons in Ireland
Total Publications: 7
 
4
Fergal J O'Brien
Royal College of Surgeons in Ireland
Total Publications: 265
 
5
Conn L Hastings
Royal College of Surgeons in Ireland
Total Publications: 11
 
6
Adolfo López-Noriega
Royal College of Surgeons in Ireland
Total Publications: 10