Type

Journal Article

Authors

Mario Ali Fares

Subjects

Agriculture & Food Science

Topics
this review the ever lasting the design and development generalizing methods new genomes comparative genomics exceptions this fact their genomic dynamics peculiarities the different tools a daily bases insects the overwhelming list computational biology data noise free living organisms endosymbiotic bacteria a real tantalizing challenge bioinformatics uch methods many advances the general patterns difficulties such endeavor the postgenomic era patterns compromise

Computational Biology Methods and Their Application to the Comparative Genomics of Endocellular Symbiotic Bacteria of Insects (2009)

Abstract Comparative genomics has become a real tantalizing challenge in the postgenomic era. This fact has been mostly magnified by the plethora of new genomes becoming available in a daily bases. The overwhelming list of new genomes to compare has pushed the field of bioinformatics and computational biology forward toward the design and development of methods capable of identifying patterns in a sea of swamping data noise. Despite many advances made in such endeavor, the ever-lasting annoying exceptions to the general patterns remain to pose difficulties in generalizing methods for comparative genomics. In this review, we discuss the different tools devised to undertake the challenge of comparative genomics and some of the exceptions that compromise the generality of s uch methods. We focus on endosymbiotic bacteria of insects because of their genomic dynamics peculiarities when compared to free-living organisms
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Full list of authors on original publication

Mario Ali Fares

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Mario Ali Fares
Trinity College Dublin
Total Publications: 43