Type

Journal Article

Authors

Paula Meleady
Michael Moriarty
Martin Clynes
Gerard McVey
Michael Henry
Orla Coleman

Subjects

Medicine & Nursing

Topics
novel the disease progression pancreatic cancer clinical early diagnosis search proteomic biomarkers novel targets

Proteomic strategies in the search for novel pancreatic cancer biomarkers and drug targets: recent advances and clinical impact. (2016)

Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers; despite a low incidence rate it is the fourth leading cause of cancer-related death in the world. Improvement of the diagnosis, prognosis and treatment remains the main focus of pancreatic cancer research. Rapid developments in proteomic technologies has improved our understanding of the pancreatic cancer proteome. Here, the authors summarise the recent proteomic strategies undertaken in the search for: novel biomarkers for early diagnosis, pancreatic cancer-specific proteins which may be used for novel targeted therapies and proteins which may be useful for monitoring disease progression post-therapy. Recent advances and findings discussed here provide great promise of having a significant clinical impact and improving the outcome of patients with this malignancy.
Collections Ireland -> Dublin City University -> PubMed

Full list of authors on original publication

Paula Meleady, Michael Moriarty, Martin Clynes, Gerard McVey, Michael Henry, Orla Coleman

Experts in our system

1
Paula Meleady
Dublin City University
Total Publications: 95
 
2
Michael Moriarty
Dublin City University
Total Publications: 8
 
3
Martin Clynes
Dublin City University
Total Publications: 209
 
4
Michael Henry
Dublin City University
Total Publications: 78
 
5
Orla Coleman
Dublin City University
Total Publications: 6