Type

Journal Article

Authors

M Helena Vasconcelos
Robert O'Connor
Raquel T Lima
Michael Henry
Paula Meleady
Hugo Seca
Diana Sousa
Alessio Di Luca
Vanessa Lopes-Rodrigues

Subjects

Medicine & Nursing

Topics
lung cancer cells myeloid cells minimally invasive cancer patients content analysis small cell lung cancer body fluids non small cell lung

Data supporting the shedding of larger extracellular vesicles by multidrug resistant tumour cells. (2015)

Abstract To date, there are no simple and minimally invasive methods to diagnose MDR. Extracellular vesicles (EVs) are shed by all cells, carry a specific cargo from the donor cells and are present in several body fluids, which means that they can potentially be easily collected from cancer patients and become the source of biomarkers to diagnose cancer. This data article contains a full list of the proteins identified in the EVs shed by an isogenic pair of chronic myeloid leukaemia cells (MDR cells and their drug-sensitive counterparts) by LC/MS/MS analysis, together with their GeneOntology analysis. In addition, it also contains data from protein content analysis and Dynamic light scattering count-rate events of the referred EVs as well as of the EVs shed from an isogenic pair of non-small cell lung cancer cells (MDR cells and their drug-sensitive counterparts). The interpretation of the data presented in this article and further extensive insights can be found in "Multidrug resistant tumour cells shed more microvesicles-like EVs and less exosomes than their drug-sensitive counterpart cells" [1].
Collections Ireland -> Dublin City University -> PubMed

Full list of authors on original publication

M Helena Vasconcelos, Robert O'Connor, Raquel T Lima, Michael Henry, Paula Meleady, Hugo Seca, Diana Sousa, Alessio Di Luca, Vanessa Lopes-Rodrigues

Experts in our system

1
M Helena Vasconcelos
Dublin City University
 
2
Robert O'Connor
Dublin City University
Total Publications: 74
 
3
Raquel T Lima
Dublin City University
Total Publications: 3
 
4
Michael Henry
Dublin City University
Total Publications: 99
 
5
Paula Meleady
Dublin City University
Total Publications: 115
 
6
Alessio Di Luca
Dublin City University
Total Publications: 3
 
7
Vanessa Lopes-Rodrigues
Dublin City University
Total Publications: 3