Type

Journal Article

Authors

David R Cotter
Toru Moriguchi
Gerard Cagney
Kieran Wynne
Melanie Focking
Akiko Harauma
Caitriona Scaife
Jane A English

Subjects

Biochemistry

Topics
mass spectrometry mitochondrial protein fatty acid free hippocampus mouse omega 3 quantitative analysis

Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation. (2015)

Abstract This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article "Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus" (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given.
Collections Ireland -> Royal College of Surgeons in Ireland -> PubMed

Full list of authors on original publication

David R Cotter, Toru Moriguchi, Gerard Cagney, Kieran Wynne, Melanie Focking, Akiko Harauma, Caitriona Scaife, Jane A English

Experts in our system

1
David R Cotter
Royal College of Surgeons in Ireland
Total Publications: 56
 
2
Gerard Cagney
Royal College of Surgeons in Ireland
Total Publications: 54
 
3
Kieran Wynne
Royal College of Surgeons in Ireland
Total Publications: 45
 
4
Melanie Focking
Royal College of Surgeons in Ireland
 
5
Caitriona Scaife
Royal College of Surgeons in Ireland
Total Publications: 13
 
6
Jane A English
Royal College of Surgeons in Ireland
Total Publications: 24