Type

Journal Article

Authors

Thomas Frodl
James Meaney
Michael Gill
Andrew Fagan
Katherine Johnson
John Kelly
Diane Mullins
Gary Donohoe
Aisling Mulligan
Norbert Skokauskas
and 3 others

Subjects

Psychiatry

Topics
reversal learning diagnosis progression childhood symptom decision making adhd adulthood

Childhood-Diagnosed ADHD, Symptom Progression, and Reversal Learning in Adulthood. (2016)

Abstract ADHD persists in up to 60% into adulthood, and the reasons for persistence are not fully understood. The objective of this study was to characterize the neurofunctional basis of decision making in those with a childhood diagnosis of ADHD with either persistent or remitted symptoms in adulthood versus healthy control participants. Thirty-two adults diagnosed with ADHD as children were split into persistent (n = 18) or remitted (n = 14) ADHD groups. Their neural activity and neurofunctional connectivity during a probabilistic reversal learning task were compared with 32 healthy controls. Remitters showed significantly higher neural connectivity in final reversal error and probabilistic error conditions, and persisters depict higher neural connectivity in reversal errors than controls at a family-wise error (FWE) corrected whole-brain corrected threshold. Remitters may have utilized higher neural connectivity than controls to make successful decisions. Also, remitters may have utilized compensatory strategies to override any potential underlying ADHD deficits.
Collections Ireland -> Trinity College Dublin -> PubMed

Full list of authors on original publication

Thomas Frodl, James Meaney, Michael Gill, Andrew Fagan, Katherine Johnson, John Kelly, Diane Mullins, Gary Donohoe, Aisling Mulligan, Norbert Skokauskas and 3 others

Experts in our system

1
Thomas Frodl
Trinity College Dublin
Total Publications: 58
 
2
James Meaney
Trinity College Dublin
Total Publications: 25
 
3
Michael Gill
Trinity College Dublin
Total Publications: 260
 
4
Andrew John Fagan
Trinity College Dublin
Total Publications: 70
 
5
Katherine Johnson
Trinity College Dublin
Total Publications: 29
 
6
Gary Donohoe
Trinity College Dublin
Total Publications: 130
 
7
Aisling Mulligan
Trinity College Dublin
Total Publications: 10
 
8
Norbert Skokauskas
Trinity College Dublin
Total Publications: 12