Type

Journal Article

Authors

Douwe van Sinderen
Thijs Kouwen
Jean-Paul Noben
Laurens Hanemaaijer
Horst Neve
Jennifer Mahony
Brian McDonnell

Subjects

Agriculture & Food Science

Topics
group a streptococcus novel the environment bacteriophages protein binding lactic acid bacterium architecture dairy industry

Identification and Analysis of a Novel Group of Bacteriophages Infecting the Lactic Acid Bacterium Streptococcus thermophilus. (2016)

Abstract We present the complete genome sequences of four members of a novel group of phages infecting Streptococcus thermophilus, designated here as the 987 group. Members of this phage group appear to have resulted from genetic exchange events, as evidenced by their "hybrid" genomic architecture, exhibiting DNA sequence relatedness to the morphogenesis modules of certain P335 group Lactococcus lactis phages and to the replication modules of S. thermophilus phages. All four identified members of the 987 phage group were shown to elicit adsorption affinity to both their cognate S. thermophilus hosts and a particular L. lactis starter strain. The receptor binding protein of one of these phages (as a representative of this novel group) was defined using an adsorption inhibition assay. The emergence of a novel phage group infecting S. thermophilus highlights the continuous need for phage monitoring and development of new phage control measures. Phage predation of S. thermophilus is an important issue for the dairy industry, where viral contamination can lead to fermentation inefficiency or complete fermentation failure. Genome information and phage-host interaction studies of S. thermophilus phages, particularly those emerging in the marketplace, are an important part of limiting the detrimental impact of these viruses in the dairy environment.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Douwe van Sinderen, Thijs Kouwen, Jean-Paul Noben, Laurens Hanemaaijer, Horst Neve, Jennifer Mahony, Brian McDonnell

Experts in our system

1
Douwe van Sinderen
University College Cork
Total Publications: 144
 
2
Thijs R. Kouwen
University College Cork
Total Publications: 10
 
3
Jean-Paul Noben
University College Cork
Total Publications: 13
 
4
Laurens Hanemaaijer
University College Cork
Total Publications: 10
 
5
Horst Neve
University College Cork
Total Publications: 41
 
6
Jennifer Mahony
University College Cork
Total Publications: 87
 
7
Brian McDonnell
University College Cork
Total Publications: 6