Type

Journal Article

Authors

Roy D Sleator
William J Snelling
Colin Hill
Cormac G M Gahan
Roland F Hoffmann
Eamonn P Culligan
Shauna M Keane

Subjects

Biochemistry

Topics
real time transcription listeria monocytogenes single phenotype mutation dna expression

Shedding light on betL*: pPL2-lux mediated real-time analysis of betL* expression in Listeria monocytogenes. (2016)

Abstract We propose a mechanism of action for the betL* mutation which is based on DNA topology. Removing a single thymine residue from the betL σ(A) promoter's -10 and -35 spacer results in a 'twist'-mediated activation of transcription which accounts for the osmotolerance phenotype observed for strains expressing betL*.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Roy D Sleator, William J Snelling, Colin Hill, Cormac G M Gahan, Roland F Hoffmann, Eamonn P Culligan, Shauna M Keane

Experts in our system

1
Roy D. Sleator
University College Cork
Total Publications: 44
 
2
Colin Hill
University College Cork
Total Publications: 351
 
3
Cormac G M Gahan
University College Cork
Total Publications: 109
 
4
Eamonn P Culligan
University College Cork
Total Publications: 13