Type

Journal Article

Authors

Anne P Nugent
Janette Walton
Albert Flynn
Michael J Gibney
Niamh F C Devlin
Dan J Duff
Jack F Bloomfield
Breige A McNulty
Lorraine Brennan
Kaifeng Li

Subjects

Agriculture & Food Science

Topics
k means cluster analysis fatty acid pattern analysis linoleic acid study habits national nutrition survey polyunsaturated fatty acids dietary intake

Plasma fatty acid patterns reflect dietary habits and metabolic health: a cross-sectional study. (2015)

Abstract Using pattern analysis, we investigated the relationship between plasma fatty acid patterns, dietary intake, and biomarkers of metabolic health using data from the Irish National Adult Nutrition Survey. Plasma fatty acid patterns were derived from 26 plasma fatty acids using k-means cluster analysis. Four clusters were identified, each with a distinct fatty acid profile. Cluster 1 included high proportions of linoleic acid (LA) and low proportions of stearic acid (SA); cluster 2 was higher in n-3 polyunsaturated fatty acids and SA; the profile of cluster 3 was higher in very-long-chain saturated fatty acid (VLCSFA) and lower in α-linolenic acid (ALA) (cluster 3); while cluster 4 was higher in fatty acids related to de-novo lipogenesis and 20:3n-6 and lower in LA (cluster 4). In general, cluster 4 was associated with adverse metabolic profile and higher metabolic risk (P ༜ 0.033). Clusters 2 and 3 were associated with healthier and protective phenotypes (P ༜ 0.033). Distinct fatty acid patterns were identified which were related to demographics, dietary habits and metabolic profile. A pattern higher in VLCSFA and lower in ALA was associated with healthier metabolic outcome. This article is protected by copyright. All rights reserved.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Anne P Nugent, Janette Walton, Albert Flynn, Michael J Gibney, Niamh F C Devlin, Dan J Duff, Jack F Bloomfield, Breige A McNulty, Lorraine Brennan, Kaifeng Li

Experts in our system

1
Anne P Nugent
University College Cork
 
2
Janette Walton
University College Cork
Total Publications: 79
 
3
Albert Flynn
University College Cork
Total Publications: 83
 
4
Michael J Gibney
University College Dublin
Total Publications: 102
 
5
Niamh F C Devlin
University College Cork
 
6
Dan J Duff
University College Cork
 
7
Jack F Bloomfield
University College Cork
 
8
Breige A McNulty
University College Cork
 
9
Lorraine Brennan
University College Dublin
Total Publications: 166
 
10
Kaifeng Li
University College Cork