Type

Journal Article

Authors

Eileen R Gibney
Anne P Nugent
Lorraine Brennan
Daniel J Duff
Frederick J Bloomfield
Kaifeng Li
Breige A McNulty
Frank J Monahan
Yang Zhao

Subjects

Veterinary

Topics
dietary intake fatty acids plasma high performance liquid chromatography national nutrition survey eicosapentaenoic acid mass spectrometry vitamin e

Plasma n-3 polyunsaturated fatty status and its relationship with vitamin E intake and plasma level. (2015)

Abstract The aim of the study was to investigate habitual vitamin E intake and plasma α-tocopherol concentration and their relationship with plasma fatty acid profile in a healthy adult population. Vitamin E and fatty acid intake data were determined from the National Adult Nutrition Survey. Plasma α- and γ-tocopherol concentrations were quantified by high-performance liquid chromatography and the percentage of fatty acids in plasma by gas chromatography coupled with mass spectrometry. Participants (n = 601) were divided into vitamin E intake quartiles and plasma α-tocopherol quartiles, and differences in fatty acid intake and plasma fatty acid profile were analyzed by a general linear model. Dietary intake data showed that as vitamin E intake increased, intakes of total polyunsaturated fatty acid (PUFA) and α-linolenic acid increased significantly (p < 0.001), but eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) did not. After adjusting for fatty acid intake, vitamin E intake was positively related to plasma n-3 PUFA (EPA and DHA) levels and plasma n-3/n-6 PUFA ratio. Plasma α-tocopherol concentration was positively related to the percentage of plasma total PUFA, n-3 PUFA and EPA and inversely related to the percentage of plasma n-6 PUFA. The study illustrates that there are statistical relationships between plasma fatty acid profile and both vitamin E intake and plasma α-tocopherol concentration. Vitamin E may play a role in the maintenance of plasma n-3 PUFA profile in humans with consequent desirable health effects.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

Eileen R Gibney, Anne P Nugent, Lorraine Brennan, Daniel J Duff, Frederick J Bloomfield, Kaifeng Li, Breige A McNulty, Frank J Monahan, Yang Zhao

Experts in our system

1
Eileen R Gibney
University College Dublin
Total Publications: 98
 
2
Anne P Nugent
University College Cork
 
3
Lorraine Brennan
University College Dublin
Total Publications: 166
 
4
Breige A McNulty
University College Cork
 
5
F.J. Monahan
University College Dublin
Total Publications: 71