Type

Journal Article

Authors

Avelino Alvarez-Ordóñez
Colin Hill
Paul D. Cotter
Laura M. Coughlan

Subjects

Agriculture & Food Science

Topics
food safety novel the this review gene expression quorum sensing food processing biofilm quorum sensing inhibitors science foundation ireland sfi control strategies food industry food population density

New weapons to fight old enemies: novel strategies for the (bio)control of bacterial biofilms in the food industry (2016)

Abstract Biofilms are microbial communities characterized by their adhesion to solid surfaces and the production of a matrix of exopolymeric substances, consisting of polysaccharides, proteins, DNA and lipids, which surround the microorganisms lending structural integrity and a unique biochemical profile to the biofilm. Biofilm formation enhances the ability of the producer/s to persist in a given environment. Pathogenic and spoilage bacterial species capable of forming biofilms are a significant problem for the healthcare and food industries, as their biofilm-forming ability protects them from common cleaning processes and allows them to remain in the environment post-sanitation. In the food industry, persistent bacteria colonize the inside of mixing tanks, vats and tubing, compromising food safety and quality. Strategies to overcome bacterial persistence through inhibition of biofilm formation or removal of mature biofilms are therefore necessary. Current biofilm control strategies employed in the food industry (cleaning and disinfection, material selection and surface preconditioning, plasma treatment, ultrasonication, etc.), although effective to a certain point, fall short of biofilm control. Efforts have been explored, mainly with a view to their application in pharmaceutical and healthcare settings, which focus on targeting molecular determinants regulating biofilm formation. Their application to the food industry would greatly aid efforts to eradicate undesirable bacteria from food processing environments and, ultimately, from food products. These approaches, in contrast to bactericidal approaches, exert less selective pressure which in turn would reduce the likelihood of resistance development. A particularly interesting strategy targets quorum sensing systems, which regulate gene expression in response to fluctuations in cell-population density governing essential cellular processes including biofilm formation. This review article discusses the problems associated with bacterial biofilms in the food industry and summarizes the recent strategies explored to inhibit biofilm formation, with special focus on those targeting quorum sensing.
Collections Ireland -> Teagasc -> Food Biosciences
Ireland -> Teagasc -> Food Biosciences
Ireland -> Teagasc -> Food Quality & Sensory Science
Ireland -> University College Cork -> Microbiology
Ireland -> Teagasc -> Food Quality & Sensory Science
Ireland -> Teagasc -> Food Programme
Ireland -> University College Cork -> Research Institutes and Centres
Ireland -> University College Cork -> Microbiology - Journal Articles
Ireland -> University College Cork -> APC Microbiome Institute
Ireland -> University College Cork -> College of Science, Engineering and Food Science
Ireland -> Teagasc -> Food Programme
Ireland -> University College Cork -> APC Microbiome Institute- Journal Articles

Full list of authors on original publication

Avelino Alvarez-Ordóñez, Colin Hill, Paul D. Cotter, Laura M. Coughlan

Experts in our system

2
Colin Hill
University College Cork
Total Publications: 351
 
3
Paul D. Cotter
Teagasc
Total Publications: 253