Type

Journal Article

Authors

Douwe van Sinderen
Kieran N. Kilcawley
Jennifer Mahony
Francesca Bottacini
Philip Kelleher

Subjects

Agriculture & Food Science

Topics
lactic acid lactococcus lactis functional genomics comparative genomics genomics pan genome smrt sequencing science foundation ireland sfi niche adaptation

Comparative and functional genomics of the Lactococcus lactis taxon; insights into evolution and niche adaptation (2017)

Abstract Background: Lactococcus lactis is among the most widely studied lactic acid bacterial species due to its long history of safe use and economic importance to the dairy industry, where it is exploited as a starter culture in cheese production. Results: In the current study, we report on the complete sequencing of 16 L. lactis subsp. lactis and L. lactis subsp. cremoris genomes. The chromosomal features of these 16 L. lactis strains in conjunction with 14 completely sequenced, publicly available lactococcal chromosomes were assessed with particular emphasis on discerning the L. lactis subspecies division, evolution and niche adaptation. The deduced pan-genome of L. lactis was found to be closed, indicating that the representative data sets employed for this analysis are sufficient to fully describe the genetic diversity of the taxon. Conclusions: Niche adaptation appears to play a significant role in governing the genetic content of each L. lactis subspecies, while (differential) genome decay and redundancy in the dairy niche is also highlighted.
Collections Ireland -> Teagasc -> Food Biosciences
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Ireland -> Teagasc -> Food Biosciences
Ireland -> Teagasc -> Food Quality & Sensory Science
Ireland -> University College Cork -> Microbiology
Ireland -> Teagasc -> Food Quality & Sensory Science
Ireland -> Teagasc -> Food Programme
Ireland -> University College Cork -> Research Institutes and Centres
Ireland -> University College Cork -> Microbiology - Journal Articles
Ireland -> University College Cork -> APC Microbiome Institute
Ireland -> University College Cork -> College of Science, Engineering and Food Science
Ireland -> Teagasc -> Food Programme
Ireland -> Teagasc -> Other Teagasc Research
Ireland -> University College Cork -> APC Microbiome Institute- Journal Articles
Ireland -> Teagasc -> Teagasc publications in Biomed Central

Full list of authors on original publication

Douwe van Sinderen, Kieran N. Kilcawley, Jennifer Mahony, Francesca Bottacini, Philip Kelleher

Experts in our system

1
Douwe van Sinderen
University College Cork
Total Publications: 144
 
2
Kieran N. Kilcawley
Teagasc
Total Publications: 49
 
3
Jennifer Mahony
University College Cork
Total Publications: 87
 
4
Francesca Bottacini
University College Cork
Total Publications: 32
 
5
Philip Kelleher
University College Cork