Type

Journal Article

Authors

Gary Donohoe
Aiden Corvin
Michael Gill
Emma Jane Rose
Derek Morris
April Hargreaves

Subjects

Psychology

Topics
genome wide association studies cognitive function cognition patients zinc finger social cognition nationality irish psychology

Poster #116 ZNF804A AND SOCIAL COGNITION IN PATIENTS WITH SCHIZOPHRENIA AND HEALTHY PARTICIPANTS (2012)

Abstract The Zinc Finger Protein 804A gene (ZNF804A) has been impli- cated as a psychosis/schizophrenia susceptibility gene by several genome wide association studies (Sullivan et al, 2008; O Donovan et al, 2008; Shi et al, 2009; International Schizophrenia Consortium et al, 2009). The identified “A” risk allele at ZNF804A rs1344706 was not associated with variation in cognitive function in independent samples of patients and controls (Walters et al, 2010). It has been associated with poorer social cognitive function in an fMRI study of theory of mind in healthy controls by Walter et al (2010). METHODS: The present study tested whether the same risk allele at ZNF804A was associated with variation on behavioural measures of social cognition in both patients with schizophrenia and healthy controls. These tasks consisted of measures of theory of mind (The Hinting Task and the Reading the eyes in the mind task) and attributional style (the Internal, Personal and Situational Attributions Questionnaire (IPSAQ)). Participants comprised 313 DSM-IV diagnosed psychotic patients, and 126 unrelated healthy controls, all of Irish nationality, grouped according to ZNF804A genotype(AAvsACvsCC).
Collections Ireland -> National College of Ireland -> Subject = B Philosophy. Psychology. Religion
Ireland -> National College of Ireland -> Type = Article
Ireland -> National College of Ireland -> Subject = B Philosophy. Psychology. Religion: Psychology
Ireland -> National College of Ireland -> Status = Published
Ireland -> National College of Ireland -> Subject = B Philosophy. Psychology. Religion: Psychology: Cognition

Full list of authors on original publication

Gary Donohoe, Aiden Corvin, Michael Gill, Emma Jane Rose, Derek Morris, April Hargreaves

Experts in our system

1
Gary Donohoe
Trinity College Dublin
Total Publications: 130
 
2
Aiden Corvin
Trinity College Dublin
Total Publications: 190
 
3
Michael Gill
Trinity College Dublin
Total Publications: 260
 
4
Emma Jane Rose
Trinity College Dublin
Total Publications: 19
 
5
Derek Morris
Trinity College Dublin
Total Publications: 150
 
6
April Hargreaves
Trinity College Dublin
Total Publications: 27