Type

Other / n/a

Authors

Amar Agha
Mary Leader
Derval Royston
Diarmuid Smith
Christopher J Thompson
Martina Morrin
Frank Keeling
Arnold DK Hill
Mohammed Al-Mousa
Patrick Hillery
and 3 others

Subjects

Medicine & Nursing

Topics
tertiary care surgery clinical assessment medicine and health sciences thyroid nodule biopsy fine needle thyroid cytology fine needle aspiration

Utility of repeat cytological assessment of thyroid nodules initially classified as benign: clinical insights from multidisciplinary care in an Irish tertiary referral centre. (2016)

Abstract BACKGROUND: Fine needle aspiration biopsy (FNAB) is the tool of choice for evaluating thyroid nodules with the majority classified as benign following initial assessment. However, concern remains about false negative results and some guidelines have recommended routine repeat aspirates. We aimed to assess the utility of routine repeat FNAB for nodules classified as benign on initial biopsy and to examine the impact of establishing a multidisciplinary team for the care of these patients.METHODS: We performed a retrospective review of 400 consecutive patients (413 nodules) who underwent FNAB of a thyroid nodule at our hospital between July 2008 and July 2011. Data recorded included demographic, clinical, histological and radiological variables.RESULTS: Three hundred and fifty seven patients (89 %) were female. Median follow-up was 5.5 years. Two hundred and fifty eight (63 %) nodules were diagnosed as benign. The rate of routine repeat biopsy increased significantly over the time course of the study (p for trend = 0.012). Nine Thy 2 nodules were classified differently on the basis of routine repeat biopsy; one patient was classified as malignant on repeat biopsy and was diagnosed with papillary thyroid carcinoma. Eight were classified as a follicular lesions on repeat biopsy-six diagnosed as benign following lobectomy; two declined lobectomy and were followed radiologically with no nodule size increase.CONCLUSIONS: The false negative rate of an initial benign cytology result, from a thyroid nodule aspirate, is low. In the setting of an experienced multidisciplinary thyroid team, routine repeat aspiration is not justified.
Collections Ireland -> Royal College of Surgeons in Ireland -> Pathology Articles
Ireland -> Royal College of Surgeons in Ireland -> Department of Pathology
Ireland -> Royal College of Surgeons in Ireland -> Department of Surgery
Ireland -> Royal College of Surgeons in Ireland -> Surgery Articles

Full list of authors on original publication

Amar Agha, Mary Leader, Derval Royston, Diarmuid Smith, Christopher J Thompson, Martina Morrin, Frank Keeling, Arnold DK Hill, Mohammed Al-Mousa, Patrick Hillery and 3 others

Experts in our system

1
Amar Agha
Royal College of Surgeons in Ireland
Total Publications: 14
 
2
M Leader
Royal College of Surgeons in Ireland
 
3
Derval Royston
Royal College of Surgeons in Ireland
Total Publications: 3
 
4
Diarmuid Smith
Dublin City University
Total Publications: 39
 
5
Christopher J Thompson
Dublin City University
 
6
Arnold D K Hill
Royal College of Surgeons in Ireland
Total Publications: 110