Type

Journal Article

Authors

Ashley J Adamson
John C Mathers
Julie A Lovegrove
Wim H M Saris
J Alfredo Martinez
Yannis Manios
Hannelore Daniel
Christian A Drevon
Thomas E Gundersen
Iwona Traczyk
and 20 others

Subjects

Veterinary

Topics
dairy products chain length dried blood spots intra class correlation sensitivity pentadecanoic acid dairy intake european fatty acids heptadecanoic acid dietary change blood regression analysis biomarkers

Within-person reproducibility and sensitivity to dietary change of C15:0 and C17:0 levels in dried blood spots: data from the European Food4Me Study (2017)

Abstract ScopePrevious work highlighted the potential of odd-chain length saturated fatty acids as potential markers of dairy intake. The aim of this study was to assess the reproducibility of these biomarkers and their sensitivity to changes in dairy intake.Methods and ResultsFatty acid profiles and dietary intakes from food frequency questionnaires (FFQs) were measured three times over six months in the Food4Me Study. Reproducibility was explored through intra-class correlation coefficients (ICCs) and within-subject coefficients of variation (WCV). Sensitivity to changes in diet was examined using regression analysis. C15:0 blood levels showed high correlation over time (ICC: 0.62, 95% CI: 0.57, 0.68), however, the ICC for C17:0 was much lower (ICC: 0.32, 95% CI: 0.28, 0.46). The WCV for C15:0 was 16.6% and that for C17:0 was 14.6%. There were significant associations between changes in intakes of total dairy, high-fat dairy, cheese and butter and C15:0; and change in intakes of high-fat dairy and cream and C17:0.ConclusionsResults provide evidence of reproducibility of C15:0 levels over time and sensitivity to change in intake of high-fat dairy products with results comparable to the well-established biomarker of fish intake (EPA+DHA).
Collections Ireland -> University College Dublin -> School of Agriculture and Food Science
Ireland -> University College Dublin -> Agriculture and Food Science Research Collection

Full list of authors on original publication

Ashley J Adamson, John C Mathers, Julie A Lovegrove, Wim H M Saris, J Alfredo Martinez, Yannis Manios, Hannelore Daniel, Christian A Drevon, Thomas E Gundersen, Iwona Traczyk and 20 others

Experts in our system

1
John C Mathers
University College Dublin
Total Publications: 33
 
2
Julie A Lovegrove
University College Dublin
Total Publications: 46
 
3
Wim H M Saris
University College Dublin
Total Publications: 39
 
4
J Alfredo Martinez
University College Dublin
Total Publications: 32
 
5
Yannis Manios
University College Dublin
Total Publications: 38
 
6
Hannelore Daniel
University College Dublin
Total Publications: 33
 
7
Christian A Drevon
University College Dublin
Total Publications: 39