Type

Conference Proceedings

Authors

Dermot Diamond
Shirley Coyle
Larisa Florea
Jennifer Deignan

Subjects

Chemistry

Topics
chemistry exercise electrochemistry contactless conductivity detection contactless conductivity sweat monitoring health cystic fibrosis

Contactless conductivity sensor for wearable sweat monitoring (2016)

Abstract Analysis of sweat offers a wealth of information related to hydration, nutrition, and athletic performance. The conductivity of sweat can be directly related to sodium chloride concentration, as these are the most abundant electrolyte ions present in sweat [1]. Individuals affected by cystic fibrosis contain a higher concentration of Cl- ions in their sweat. Prescription medications for the disease reduce Cl- concentrations in sweat, and as a result, the efficacy of these medications can be monitored non-invasively with sweat collection. In previous work, we have demonstrated the use of capacitively coupled contactless conductivity detection (C4D) for testing the response of commercial gold microelectrodes to NaCl solutions using multiple sampling platforms [2]. This work presents the optimization of channel and sampling volumes to calculate and minimize the sensor’s response time for applications in wearable sweat sensing. In preparation for on-body testing, the functionality of the chip was optimized for relevant flow rates of sweat. Sweat rate can vary drastically depending upon the subject and body part. Additionally, those affected by cystic fibrosis have difficulty exercising for extended periods of time. Due to these restrictions, the volume of sweat needed to produce a signal is of critical importance. In this work, PDMS microchannels were created which minimized platform volume for on-body analysis. Using varying concentrations of NaCl solutions (10 mM - 130 mM) and the average flow rates for the arm (730 g/m2h), back (797 g/m2h) and forehead (894 g/m2h), a calibration curve was created and the average response time was calculated for each body location. Finally, tests were completed with artificial sweat and compared to the calibration curves. [1] Lezana, J. L.; Vargas, M. H.; Karam-Bechara, J.; Aldana, R. S. and Furuya, E. Y. J. Cyst. Fibros., 2003, (pp. 1-7). [2] Deignan, J.; Florea, L; Coyle, S; and Diamond, D. MicroTAS 2014, 2014 (pp. 2184-2186). Science foundation Ireland under the Insight initiative, grant SFI/12/RC/2289
Collections Ireland -> Dublin City University -> Publication Type = Conference or Workshop Item
Ireland -> Dublin City University -> Subject = Physical Sciences: Chemistry
Ireland -> Dublin City University -> Subject = Medical Sciences: Health
Ireland -> Dublin City University -> Subject = Physical Sciences: Electrochemistry
Ireland -> Dublin City University -> Status = Unpublished
Ireland -> Dublin City University -> Subject = Medical Sciences: Exercise
Ireland -> Dublin City University -> DCU Faculties and Centres = DCU Faculties and Schools: Faculty of Science and Health: School of Chemical Sciences
Ireland -> Dublin City University -> DCU Faculties and Centres = Research Initiatives and Centres: National Centre for Sensor Research (NCSR)
Ireland -> Dublin City University -> DCU Faculties and Centres = Research Initiatives and Centres: INSIGHT Centre for Data Analytics

Full list of authors on original publication

Dermot Diamond, Shirley Coyle, Larisa Florea, Jennifer Deignan

Experts in our system

1
Dermot Diamond
Dublin City University
Total Publications: 607
 
2
Shirley Coyle
Dublin City University
Total Publications: 86
 
3
Larisa Florea
Dublin City University
Total Publications: 163
 
4
Jennifer Deignan
Dublin City University
Total Publications: 12