Type

Journal Article

Authors

Lisa Mellon
Richard W Costello
Richard B Reilly
Gerard J Molloy
Garrett Greene
Kathleen Bennett
Imran Sulaiman
Frank Doyle
Catherine Moran

Subjects

Psychology

Topics
lung function quality of life prospective study observational study self report compliance health status chronic obstructive pulmonary disease copd

The INCA(TM) (Inhaler Compliance Assessment(TM)): A comparison with established measures of adherence. (2017)

Abstract To compare the Inhaler Compliance Assessment(TM) (INCA(TM)), a novel audio-recording device objectively measuring timing and proficiency of inhaler use, against established adherence measures, and explore its discriminant and predictive validity. Prospective observational study; 184 chronic obstructive pulmonary disease (COPD) patients used an INCA(TM)-enabled salmeterol/fluticasone inhaler for one-month post-hospital discharge. INCA(TM) (Attempted, Attempted Interval, Actual) adherence correlated with Doses Used Rate, self-reported adherence and prescription refill for concurrent validity. Discriminant validity for reason for admission, cognition and lung function; predictive validity for health status and quality-of-life. Rates of Attempted, Attempted Interval and Actual adherence were 59, 47 and 23%, respectively. Only 7% of participants had Actual adherence >80%. INCA(TM) variables significantly correlated with Doses Used Rate but not with self-report; Attempted and Attempted Interval were weakly associated with prescription refill. Higher cognitive and lung functioning groups had better INCA(TM) adherence. Attempted and Attempted Interval predicted health status, while Doses Used Rate predicted quality-of-life. INCA(TM) did not strongly correlate with self-report or prescription refill data. Discriminant and predictive validity demonstrated by INCA(TM) suggests the potential utility of the INCA(TM) as a method to identify intentional and unintentional adherence to inhaled medication and facilitate targeted intervention.
Collections Ireland -> National University of Ireland Galway -> PubMed

Full list of authors on original publication

Lisa Mellon, Richard W Costello, Richard B Reilly, Gerard J Molloy, Garrett Greene, Kathleen Bennett, Imran Sulaiman, Frank Doyle, Catherine Moran

Experts in our system

1
Lisa Mellon
Royal College of Surgeons in Ireland
Total Publications: 23
 
2
Richard W Costello
Royal College of Surgeons in Ireland
Total Publications: 62
 
3
Richard Reilly
Trinity College Dublin
Total Publications: 183
 
4
Gerard J Molloy
National University of Ireland Galway
Total Publications: 7
 
5
Garrett Greene
Royal College of Surgeons in Ireland
Total Publications: 6
 
6
Kathleen Bennett
Trinity College Dublin
Total Publications: 131
 
7
Imran Sulaiman
Royal College of Surgeons in Ireland
Total Publications: 24
 
8
Frank Doyle
Royal College of Surgeons in Ireland
Total Publications: 113
 
9
Catherine Nora Moran
Royal College of Surgeons in Ireland
Total Publications: 4