Type

Journal Article

Authors

Gianpiero L Cavalleri
James F Wilson
Sean Ennis
Shai Carmi
Edmund Gilbert

Subjects

History

Topics
settled people great famine irish population irish people irish travellers genetic analysis social history population structure

Genomic insights into the population structure and history of the Irish Travellers. (2016)

Abstract The Irish Travellers are a population with a history of nomadism; consanguineous unions are common and they are socially isolated from the surrounding, 'settled' Irish people. Low-resolution genetic analysis suggests a common Irish origin between the settled and the Traveller populations. What is not known, however, is the extent of population structure within the Irish Travellers, the time of divergence from the general Irish population, or the extent of autozygosity. Using a sample of 50 Irish Travellers, 143 European Roma, 2232 settled Irish, 2039 British and 6255 European or world-wide individuals, we demonstrate evidence for population substructure within the Irish Traveller population, and estimate a time of divergence before the Great Famine of 1845-1852. We quantify the high levels of autozygosity, which are comparable to levels previously described in Orcadian 1(st)/2(nd) cousin offspring, and finally show the Irish Traveller population has no particular genetic links to the European Roma. The levels of autozygosity and distinct Irish origins have implications for disease mapping within Ireland, while the population structure and divergence inform on social history.
Collections Ireland -> Royal College of Surgeons in Ireland -> PubMed

Full list of authors on original publication

Gianpiero L Cavalleri, James F Wilson, Sean Ennis, Shai Carmi, Edmund Gilbert

Experts in our system

1
Gianpiero L Cavalleri
Royal College of Surgeons in Ireland
Total Publications: 35
 
2
James F Wilson
Royal College of Surgeons in Ireland
Total Publications: 3
 
3
Sean Ennis
University College Dublin
Total Publications: 52
 
4
Edmund Gilbert
Royal College of Surgeons in Ireland
Total Publications: 3