Type

Journal Article

Authors

Joseph P. Cassidy
Colin J Bell
Hywel Ball
Tracy A Clegg
Bernadette Earley
William J Byrne
Ronan G. O'Neill
Máire C McElroy
Mìcheàl J Casey
Dónal Sammin
and 2 others

Subjects

Veterinary

Topics
respiratory syncytial virus bovine cattle animals suckling animals cattle diseases pasteurella multocida diagnosis microbiology bronchopneumonia veterinary isolation purification epidemiology polymerase chain reaction parainfluenza virus 3 bovine ireland mannheimia haemolytica immunohistochemistry autopsy

Pathogens, patterns of pneumonia, and epidemiologic risk factors associated with respiratory disease in recently weaned cattle in Ireland. (2017)

Abstract We examined the pathogens, morphologic patterns, and risk factors associated with bovine respiratory disease (BRD) in 136 recently weaned cattle ("weanlings"), 6-12 mo of age, that were submitted for postmortem examination to regional veterinary laboratories in Ireland. A standardized sampling protocol included routine microbiologic investigations as well as polymerase chain reaction and immunohistochemistry. Lungs with histologic lesions were categorized into 1 of 5 morphologic patterns of pneumonia. Fibrinosuppurative bronchopneumonia (49%) and interstitial pneumonia (48%) were the morphologic patterns recorded most frequently. The various morphologic patterns of pulmonary lesions suggest the involvement of variable combinations of initiating and compounding infectious agents that hindered any simple classification of the etiopathogenesis of the pneumonias. Dual infections were detected in 58% of lungs, with Mannheimia haemolytica and Histophilus somni most frequently recorded in concert. M. haemolytica (43%) was the most frequently detected respiratory pathogen; H. somni was also shown to be frequently implicated in pneumonia in this age group of cattle. Bovine parainfluenza virus 3 (BPIV-3) and Bovine respiratory syncytial virus (16% each) were the viral agents detected most frequently. Potential respiratory pathogens (particularly Pasteurella multocida, BPIV-3, and H. somni) were frequently detected (64%) in lungs that had neither gross nor histologic pulmonary lesions, raising questions regarding their role in the pathogenesis of BRD. The breadth of respiratory pathogens detected in bovine lungs by various detection methods highlights the diagnostic value of parallel analyses in respiratory disease postmortem investigation.
Collections Ireland -> Teagasc -> PubMed

Full list of authors on original publication

Joseph P. Cassidy, Colin J Bell, Hywel Ball, Tracy A Clegg, Bernadette Earley, William J Byrne, Ronan G. O'Neill, Máire C McElroy, Mìcheàl J Casey, Dónal Sammin and 2 others

Experts in our system

1
Joseph P. Cassidy
University College Dublin
Total Publications: 54
 
2
T A Clegg
University College Dublin
Total Publications: 46
 
3
Bernadette Earley
Teagasc
Total Publications: 114
 
4
Ronan G. O'Neill
Teagasc
Total Publications: 17
 
5
Máire C McElroy
Teagasc
Total Publications: 26
 
6
Micheal Casey
Teagasc
Total Publications: 5
 
7
D Sammin
University College Dublin
Total Publications: 13