Type

Journal Article

Authors

Lorraine Brennan
Michael J Gibney
Albert Flynn
Janette Walton
Anne P Nugent
Breige A McNulty
Eibhlin Carr
Helena Gibbons

Subjects

Agriculture & Food Science

Topics
metabolomic adult classification meat products clusters patterns cluster analysis national nutrition survey

Metabolomic-based identification of clusters that reflect dietary patterns. (2016)

Abstract Classification of subjects into dietary patterns generally relies on self-reporting dietary data which are prone to error. The aim of the present study was to develop a model for objective classification of people into dietary patterns based on metabolomic data. Dietary and urinary metabolomic data from the National Adult Nutrition Survey (NANS) was used in the analysis (n = 567). Two-step cluster analysis was applied to the urinary data to identify clusters. The subsequent model was used in an independent cohort to classify people into dietary patterns. Two distinct dietary patterns were identified. Cluster 1 was characterized by significantly higher intakes of breakfast cereals, low fat and skimmed milks, potatoes, fruit, fish and fish dishes (p < 0.05) representing a "healthy" cluster. Cluster 2 had significantly higher intakes of chips/processed potatoes, meat products, savory snacks and high-energy beverages (p < 0.05) representing an "unhealthy cluster". Classification was supported by significant differences in nutrient status (p < 0.05). Validation in an independent group revealed that 94% of subjects were correctly classified. The model developed was capable of classifying individuals into dietary patterns based on metabolomics data. Future applications of this approach could be developed for rapid and objective assignment of subjects into dietary patterns.
Collections Ireland -> University College Cork -> PubMed

Full list of authors on original publication

Lorraine Brennan, Michael J Gibney, Albert Flynn, Janette Walton, Anne P Nugent, Breige A McNulty, Eibhlin Carr, Helena Gibbons

Experts in our system

1
Lorraine Brennan
University College Dublin
Total Publications: 166
 
2
Michael J Gibney
University College Dublin
Total Publications: 102
 
3
Albert Flynn
University College Cork
Total Publications: 83
 
4
Janette Walton
University College Cork
Total Publications: 79
 
5
Anne P Nugent
University College Cork
 
6
Breige A McNulty
University College Cork
 
7
Helena Gibbons
University College Dublin